Safety data sheet
According to EC Directive 91/155/EEC
MERCK
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1. Identification of the substance/preparation and of the company/undertaking
Identification of the product
Catalogue No.: 100012
Product name: Acetone for organic trace analysis SupraSolv®

Manufacturer/supplier identification
Company: Merck Ltd.
9th Floor, Monterey Tower, 2170 New Petchburi Road, Bangkapi, Huaykwang, Bangkok 10320
Tel: (662) 308 - 0218

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2. Composition/information on ingredients
Synonyms
Dimethyl ketone ; Propanone

CAS-No.: 67-64-1 EC-Index-No.: 606-001-00-8
Molar mass: 58.08 EINECS-No.: 200-662-2
Molecular formula: C3H6O

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3. Hazards identification
Highly flammable.

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4. First aid measures
After inhalation: fresh air. If necessary apply mouth to mouth resuscitation or mechanical ventilation. Keep airways free.
After skin contact: wash off with plenty of water. Remove contaminated clothing.
After eye contact: rinse out with plenty of water for at least 10 minutes with the eyelid held wide open. Summon eye specialist.
After swallowing: immediately make victim drink plenty of water. Subsequently administer: activated charcoal (20 - 40g in 10% slurry). Risk of aspiration! Do not induce vomiting. No milk. No digestible oils. Keepairways free. Summon doctor. Laxative: sodium sulfate (1 tablespoon/ 1/4 l water). After ingestion of large amounts: gastric lavage.

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5. Fire-fighting measures
Suitable extinguishing media:
water , Powder, foam.

Special risks:
Combustible. Vapours heavier than air. Formation of explosible mixtures possible with air. Keep away from sources of ignition. Take measures to prevent electrostatic charging.

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6. Accidental release measures
Person-related precautionary measures:
Do not inhale vapours/aerosols. Ensure supply of fresh air in enclosed rooms.

Procedures for cleaning / absorption:
Take up with liquid-absorbent material (e.g. Chemizorb® ). Forward for disposal. Clean up affected area.

Additional notes:
Do not allow to enter sewerage system.

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7. Handling and storage
Handling:
Take measures to prevent electrostatic charging.

Storage:
Tightly closed. In a well-ventilated place. Keep away from sources of ignition and heat. Protected from light. At +15°C to +25°C.

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8. Exposure controls/personal protection
Specific control parameter
MAK Germany (max. workplace conc.)
Acetone 500 ml/m3 or 1200 mg/m3

Personal protective equipment:
Respiratory protection: required when vapours/aerosols are generated. Filter AX (EN 371)
Eye protection: required
Hand protection: required

Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. The resistance of the protective clothing to chemicals should be ascertained with the respective supplier.
Industrial hygiene: Immediately change contaminated clothing. Apply skin- protective barrier cream. Wash hands and face after working with substance.

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9. Physical and chemical properties
Form: liquid
Colour: colourless
Odour: characteristic
pH value not available
Viscosity dynamic (32 °C) 0.32 mPa*s
Melting temperature -95 °C
Boiling temperature 56 °C
Ignition temperature 540 °C
Flash point -20 °C
Explosion limits lower 2.5 Vol%
upper 13 Vol%
Vapour pressure (20 °C) 233 mbar
Density (20 °C) 0.79 g/cm3
Solubility in water (20 °C) soluble
log P(oct): -0.24

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10. Stability and reactivity
Conditions to be avoided
Heating.

Substances to be avoided
alkali hydroxides , halogens , halogenated hydrocarbons / alkali hydroxides , halogen-halogen compounds , oxidizing agent (i.a. CrO3 , peroxi compounds , nitric acid , nitrating acid ) , halogen oxides , alkali metals , nitrosyl compounds , metals , ethanolamine

Hazardous decomposition products
peroxides

Further information
light-sensitive ; sensitive to air ; solvent ;
unsuitable working materials: various plastics
Explosible with air in a vaporous/gaseous state.

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11. Toxicological information
Acute toxicity
LD50 (oral, rat): 5800 mg/kg

Subacute to chronic toxicity
Checks into the substance have so far not disclosed any investigations concerning possible teratogenic effects.

Further toxicological information
After inhalation of vapours: mucosal irritations In high doses: headache , salivation , nausea , vomiting , dizziness , narcosis Cannot be excluded: coma
After eye contact: Risk of corneal clouding.
After swallowing: gastrointestinal complaints headache , salivation nausea , vomiting , dizziness , narcosis , coma

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12. Ecological information
Behavior in environmental compartments:
Distribution: log P(oct):: -0.24

Ecotoxic effects:
Biological effects:
Fish toxicity: L.idus LC50: 7505 mg/l ;
Arthropods: Daphnia magna LC50: 12100 mg/l /48 h ;

Further ecologic data:
Degradability:
BOD5: 1.76 g/g ; COD: 2.07 g/g ; ThOD: 2.2 mg/l

No ecological problems are to be expected when the product is handled and used with due care and attention.

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13. Disposal considerations
Product:
There are no uniform EC Regulations for the disposal of chemicals or residues. Chemical residues generally count as special waste. The disposal of the latter is regulated in the EC member countries through corresponding laws and regulations. We recommend that you contact either the authorities in charge or approved waste disposal companies which will advise you on how to dispose of special waste.

Packaging:
Disposal in compliance with official regulations. Handle contaminated packaging in the same way as the substance itself. If not officially specified differently, non-contaminated packaging may be treated like household waste or recycled.

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14. Transport information
Transport over land ADR/RID and GGVS/GGVE (Germany)
GGVS/GGVE class: 3 Number and letter: 3b
ADR/RID class: 3 Number and letter: 3b
Name of material: 1090 ACETON

River transport ADN/ADNR
not examined

Sea transport IMDG
IMDG class: 3.1 UN-No.: 1090 Packaging group: II
Ems: 3-06 MFAG: 300
Correct technical name: ACETONE

Air transport ICAO-TI and IATA-DGR
ICAO/IATA class: 3 UN/ID-No.: 1090 Packaging group: II
Correct technical name: ACETONE

The transport regulations are cited according to international regulations and in the form applicable in Germany (GGVS/GGVE). Possible national deviations in other countries are not considered.

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15. Regulatory information
Labelling according to EC Directives
Symbol: F Highly flammable immediately and show this container or label.
R-phrases: R 11 Highly flammable.
S-phrases: S 9-16-23.2-33 Keep container in a well-ventilated place. Keep away from sources of ignition - No smoking. Do not breathe vapour. Take precautionary measures against static discharges.
EC-No.: 200-662-2 EC label

German regulations
Water pollution class 0 (generally nonpolluting substance)

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16. Other information
no information available


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