| Safety data sheet |
| According to EC Directive 91/155/EEC |
|
|
| 1. Identification of the substance/preparation and of the company/undertaking |
| Identification of the product | ||
| Catalogue No.: | 823336 | |
| Product name: | Ethylene oxide for synthesis | |
| Manufacturer/supplier identification | ||
| Company: |
Merck Ltd. 9th Floor, Monterey Tower, 2170 New Petchburi Road, Bangkapi, Huaykwang, Bangkok 10320 Tel: (662) 308 - 0218 |
|
| 2. Composition/information on ingredients |
| Synonyms |
| Oxirane |
| CAS-No.: | 75-21-8 | EC-Index-No.: | 603-023-00-X | ||
| Molar mass: | 44.05 | EINECS-No.: | 200-849-9 | ||
| Molecular formula: | C2H4O | ||||
| 3. Hazards identification |
| May cause cancer. May cause heritable genetic damage. Extremely flammable. Also toxic by inhalation. Irritating to eyes, respiratory system and skin. |
| 4. First aid measures |
|
After inhalation: fresh air. If necessary, apply mouth-to-mouth resuscitation or mechanical ventilation. Immediately summon doctor. Keep airways free. After skin contact: wash off with plenty of water. Remove contaminated clothing. After eye contact: rinse out with plenty of water for at least 10 minutes with the eyelid held wide open. Summon eye specialist. |
| 5. Fire-fighting measures |
| Suitable extinguishing media: |
| foam , powder , spray water Fire extinguisher: powder , carbon dioxide |
|
Special risks: |
| Combustible. Vapours heavier than air. Forms explosive mixtures with air at ambient temperatures. Keep away sources of ignition. |
|
Special protective equipment for fire fighting: |
| Do not stay in dangerous zone without suitable chemical protection clothing and self-contained breathing apparatus. |
|
Other information: |
| Prevent fire-fighting water from entering surface water or groundwater. |
| 6. Accidental release measures |
|
Person-related precautionary measures: Do not inhale vapours. Ensure supply of fresh air in enclosed rooms. Procedures for cleaning / absorption: Stop flow of gas, move leaking cylinder to open air if without risk. Do not inhale vapours. |
| 7. Handling and storage |
| Handling: |
| No further requirements. |
| Storage: |
|
Tightly closed. Cool. Away from combustible substances. Keep away from sources of ignition. Accessible only for authorized persons. Take measures to prevent electrostatic charging. |
| 8. Exposure controls/personal protection |
| Personal protective equipment: | |
| Respiratory protection: | required |
| Eye protection: | required |
| Hand protection: | required |
| Industrial hygiene: | Immediately change contaminated clothing. Apply skin- protective barrier cream. Wash hands and face after working with substance. Under no circumstances eat or drink at workplace. Work under hood . Do not inhale substance. |
| 9. Physical and chemical properties |
| Form: | gas | |||
| Colour: | colourless | |||
| Odour: | sweetish | |||
| pH value | (20 °C) | 7 | (saturated solution) | |
| Melting temperature | -112 °C | |||
| Boiling temperature | 11 °C | |||
| Ignition temperature | 440 °C | |||
| Flash point | -30 °C | |||
| Explosion limits | lower | 2.6 Vol% | ||
| upper | 99 Vol% | |||
| Vapour pressure | (20 °C) | 1453 hPa | ||
| Density | (20 °C) | 0.87 g/cm3 | ||
| Solubility in | water | (20 °C) | soluble | |
| ethanol | (20 °C) | soluble | ||
| ether | (20 °C) | soluble |
| 10. Stability and reactivity |
| Conditions to be avoided |
| Heating. |
| Substances to be avoided |
| alkali metals , amines , alkaline earth metals , organometallic compounds , oxidizing agent , alkalis , acids and polymerization initiators |
| Hazardous decomposition products |
| no information available |
| Further information |
| heat-sensitive ; |
| 11. Toxicological information |
| Acute toxicity |
| LD50 (oral, rat): 72 mg/kg ; |
| Subacute to chronic toxicity |
|
Animal experiments performed under conditions comparable with the workplace situation have shown the substance to be carcinogenic. A mutagenic effect has been demonstrated in animal studies on mammals, justifying the assumption that exposure of humans to the substance produces hereditary damage. |
| Further toxicological information |
|
After inhalation: Irritations of the mucous membranes, coughing, and dyspnoea. Irritations of mucous membranes in the mouth, pharynx, oesophagus and gastrointestinal tract. Nausea, vomiting Inhalation may lead to the formation of oedemas in the respiratory tract. After skin contact: burns Danger of skin absorption. After eye contact: Burns. Risk of blindness! After absorption of toxic quantities: CNS disorders , headache , narcosis , cardiovascular disorders , changes in the blood picture Toxic effect on: liver , kidneys |
| Further data |
| The product should be handled with the care usual when dealing with chemicals. |
| 12. Ecological information |
|
Ecotoxic effects: Biological effects: Toxic for aquatic organisms Hazard for drinking water supplies. Toxic effect on fish and plankton. Fish toxicity: C.auratus LC50: 90 mg/l /24 h ; L.idus LC50: > 10 mg/l ; Daphnia toxicity: Daphnia magna LC50: 137 mg/l ; aquatic organisms LC50: > 10 mg/l /96 h ; Further ecologic data: Fungicidal effect. Insecticidal effect. Degradability: BOD5: 0.06 g/g ; COD: 1.74 g/g Do not allow to enter waters, waste water, or soil! |
| 13. Disposal considerations |
| Product: |
| There are no uniform EC Regulations for the disposal of chemicals or residues. Chemical residues generally count as special waste. The disposal of the latter is regulated in the EC member countries through corresponding laws and regulations. We recommend that you contact either the authorities in charge or approved waste disposal companies which will advise you on how to dispose of special waste. |
| Packaging: |
| Disposal in compliance with official regulations. Handle contaminated packaging in the same way as the substance itself. If not officially specified differently, non-contaminated packaging may be treated like household waste or recycled. |
| 14. Transport information |
| Transport over land ADR/RID and GGVS/GGVE (Germany) | ||||
| GGVS/GGVE class: | 2 | Number and letter: | ||
| ADR/RID class: | 2 | Number and letter: | ||
| Name of material: | 1040 ETHYLENOXID | |||
| River transport ADN/ADNR | |||
| not examined | |||
| Sea transport IMDG | ||||||
| IMDG class: | 2.3 | UN-No.: | 1040 | Packaging group: | ||
| Ems: | 2-06 | MFAG: | 365 | |||
| Correct technical name: | ETHYLENE OXIDE | |||||
| Air transport ICAO-TI and IATA-DGR | |||||
| ICAO/IATA class: | 2.3/2.1 | UN/ID-No.: | 1040 | Packaging group: | |
| Correct technical name: | ETHYLENE OXIDE | ||||
| The transport regulations are cited according to international regulations and in the form applicable in Germany (GGVS/GGVE). Possible national deviations in other countries are not considered. |
| 15. Regulatory information |
| Labelling according to EC Directives | ||
| Symbol: | F+ | Extremely flammable immediately and show this container or label. |
| T | Toxic immediately and show this container or label. | |
| R-phrases: | R 45-46-12-E23-36/37/38 | May cause cancer. May cause heritable genetic damage. Extremely flammable. Also toxic by inhalation. Irritating to eyes, respiratory system and skin. |
| S-phrases: | S 53-45 | Avoid exposure - obtain special instructions before use. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
| EC-No.: | 200-849-9 | EC label |
| German regulations | ||
| Water pollution class | 2 | (polluting substance) |
| 16. Other information |
| General update. |
| Reason for alteration |
|
General update. See chapter 3 |
