| Safety data sheet |
| According to EC Directive 91/155/EEC |
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| 1. Identification of the substance/preparation and of the company/undertaking |
| Identification of the product | ||
| Catalogue No.: | 106146 | |
| Product name: | Isobutyl methyl ketone for extraction analysis ACS | |
| Manufacturer/supplier identification | ||
| Company: |
Merck Ltd. 9th Floor, Monterey Tower, 2170 New Petchburi Road, Bangkapi, Huaykwang, Bangkok 10320 Tel: (662) 308 - 0218 |
|
| 2. Composition/information on ingredients |
| Synonyms |
| Isopropylacetone ; 4-Methyl-2-pentanone ; Hexone |
| CAS-No.: | 108-10-1 | EC-Index-No.: | 606-004-00-4 | ||
| Molar mass: | 100.16 | EINECS-No.: | 203-550-1 | ||
| Molecular formula: | C6H12O | ||||
| 3. Hazards identification |
| Highly flammable. |
| 4. First aid measures |
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After inhalation: fresh air. If necessary apply mouth to mouth resuscitation or mechanical ventilation. Keep airways free. After skin contact: wash off with plenty of water. Remove contaminated clothing. After eye contact: rinse out with plenty of water for at least 10 minutes with the eyelid held wide open. Summon eye specialist. After swallowing: immediately make victim drink plenty of water. Subsequently administer: activated charcoal (20 - 40g in 10% slurry). Risk of aspiration! Do not induce vomiting. No milk. No digestible oils. Keepairways free. Summon doctor. Laxative: sodium sulfate (1 tablespoon/ 1/4 l water). After ingestion of large amounts: gastric lavage. |
| 5. Fire-fighting measures |
| Suitable extinguishing media: |
| Powder, foam. Fire extinguisher: carbon dioxide , powder |
|
Special risks: |
| Combustible. Vapours heavier than air. Formation of explosible mixtures possible with air. Keep away from sources of ignition. |
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Other information: |
| Take measures to prevent electrostatic charging. |
| 6. Accidental release measures |
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Person-related precautionary measures: Do not inhale vapours/aerosols. Procedures for cleaning / absorption: Take up with liquid-absorbent material (e.g. Chemizorb® ). Forward for disposal. Clean up affected area. Environmental-protection measures: Do not allow to enter sewerage system; risk of explosion! |
| 7. Handling and storage |
| Handling: |
| Take measures to prevent electrostatic charging. |
| Storage: |
| Tightly closed. In a well-ventilated place. Keep away from sources of ignition and heat. At +15°C to +25°C. |
| 8. Exposure controls/personal protection |
| Specific control parameter | ||
| MAK Germany (max. workplace conc.) | ||
| Hexone | 20 ml/m3 or 83 mg/m3 | |
| Personal protective equipment: | |
| Respiratory protection: | required when vapours/aerosols are generated. |
| Eye protection: | required |
| Hand protection: | required |
| Industrial hygiene: | Immediately change contaminated clothing. Apply skin- protective barrier cream. Wash hands and face after working with substance. |
| 9. Physical and chemical properties |
| Form: | liquid | |||
| Colour: | colourless | |||
| Odour: | characteristic | |||
| pH value | not available | |||
| Melting temperature | -84 °C | |||
| Boiling temperature | 116 - 118 °C | |||
| Ignition temperature | 475 °C | |||
| Flash point | 14 °C | |||
| Explosion limits | lower | 1.2 Vol% | ||
| upper | 8.0 Vol% | |||
| Vapour pressure | (20 °C) | ~ 20 mbar | ||
| Density | (20 °C) | 0.80 g/cm3 | ||
| Solubility in | water | (20 °C) | ~ 18 - 20 g/l |
| 10. Stability and reactivity |
| Conditions to be avoided |
| Heating. |
| Substances to be avoided |
| oxidizing agent |
| Hazardous decomposition products |
| no information available |
| Further information |
|
highly inflammable ; unsuitable working materials: various plastics , rubber ; Explosible with air in a vaporous/gaseous state. |
| 11. Toxicological information |
| Acute toxicity |
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LD50 (oral, rat): 2080 mg/kg LD50 (dermal, rabbit): > 16000 mg/kg |
| Subacute to chronic toxicity |
| An embryotoxic effect need not be feared when the threshold limit value is observed. |
| Further toxicological information |
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After skin contact: slight irritation symptoms Danger of skin absorption. After eye contact: vapours : irritant effect After swallowing: gastrointestinal complaints , Systemic effects: headache , inebriation , nausea , narcosis |
| 12. Ecological information |
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Ecotoxic effects: Biological effects: Toxic for aquatic organisms aquatic organisms : LC50: > 1000 mg/l /96 h ; Fish toxicity: fish LC50: 460 mg/l /24 h Daphnia toxicity: Daphnia magna LC50: 4280 mg/l /96 h Degradability: ThOD: 2.72 g/g ; BOD 4.4 Prozent of ThOD /5 d ; COD 79 Prozent of ThOD Further ecologic data: Do not allow to enter waters, waste water, or soil! |
| 13. Disposal considerations |
| Product: |
| There are no uniform EC Regulations for the disposal of chemicals or residues. Chemical residues generally count as special waste. The disposal of the latter is regulated in the EC member countries through corresponding laws and regulations. We recommend that you contact either the authorities in charge or approved waste disposal companies which will advise you on how to dispose of special waste. |
| Packaging: |
| Disposal in compliance with official regulations. Handle contaminated packaging in the same way as the substance itself. If not officially specified differently, non-contaminated packaging may be treated like household waste or recycled. |
| 14. Transport information |
| Transport over land ADR/RID and GGVS/GGVE (Germany) | ||||
| GGVS/GGVE class: | 3 | Number and letter: | 3b | |
| ADR/RID class: | 3 | Number and letter: | 3b | |
| Name of material: | 1245 METHYLISOBUTYLKETON | |||
| River transport ADN/ADNR | |||
| not examined | |||
| Sea transport IMDG | ||||||
| IMDG class: | 3.2 | UN-No.: | 1245 | Packaging group: | II | |
| Ems: | 3-07 | MFAG: | 300 | |||
| Correct technical name: | METHYL ISOBUTYL KETONE | |||||
| Air transport ICAO-TI and IATA-DGR | |||||
| ICAO/IATA class: | 3 | UN/ID-No.: | 1245 | Packaging group: | II |
| Correct technical name: | METHYL ISOBUTYL KETONE | ||||
| The transport regulations are cited according to international regulations and in the form applicable in Germany (GGVS/GGVE). Possible national deviations in other countries are not considered. |
| 15. Regulatory information |
| Labelling according to EC Directives | ||
| Symbol: | F | Highly flammable immediately and show this container or label. |
| R-phrases: | R 11 | Highly flammable. |
| S-phrases: | S 9-16-23.2-33 | Keep container in a well-ventilated place. Keep away from sources of ignition - No smoking. Do not breathe vapour. Take precautionary measures against static discharges. |
| EC-No.: | 203-550-1 | EC label |
| German regulations | ||
| Water pollution class | 1 | (slightly polluting substance) |
| 16. Other information |
| Reason for alteration |
|
Specific control parameter. Change in the chapter on first aid measures. |
