| Safety data sheet |
| According to EC Directive 91/155/EEC |
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|
| 1. Identification of the substance/preparation and of the company/undertaking |
| Identification of the product | ||
| Catalogue No.: | 820264 | |
| Product name: | 2-Chloroacetophenone for synthesis | |
| Manufacturer/supplier identification | ||
| Company: |
Merck Ltd. 9th Floor, Monterey Tower, 2170 New Petchburi Road, Bangkapi, Huaykwang, Bangkok 10320 Tel: (662) 308 - 0218 |
|
| 2. Composition/information on ingredients |
| Synonyms |
| Phenacyl chloride ; omega-Chloroacetophenone |
| CAS-No.: | 532-27-4 | EC-Index-No.: | - | ||
| Molar mass: | 154.60 | EINECS-No.: | 208-531-1 | ||
| Molecular formula: | C8H7ClO | ||||
| 3. Hazards identification |
| Toxic if swallowed. Irritating to eyes and respiratory system. May cause sensitization by skin contact. |
| 4. First aid measures |
|
After skin contact: wash off with plenty of water. Remove contaminated clothing. After eye contact: rinse out with plenty of water for at least 10 minutes with the eyelid held wide open. Summon eye specialist. After inhalation: fresh air. After swallowing: make the victim drink plenty of water, induce vomiting. Immediately summon doctor. |
| 5. Fire-fighting measures |
| Suitable extinguishing media: |
| CO2, foam, powder. |
|
Special risks: |
| Combustible. Development of hazardous combustion gases or vapours possible in the event of fire. The following may develop in event of fire: hydrochloric acid , phosgene |
| 6. Accidental release measures |
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Procedures for cleaning / absorption: Take up with liquid-absorbent material (e.g. Chemizorb® ). Forward for disposal. Clean up affected area. Do not inhale vapours. |
| 7. Handling and storage |
| Handling: |
| No further requirements. |
| Storage: |
| Tightly closed. Cool. In a well-ventilated place. |
| 8. Exposure controls/personal protection |
| Personal protective equipment: | |
| Respiratory protection: | required Filter A (acc. to DIN 3181) for vapours of organic compounds |
| Eye protection: | required |
| Hand protection: | required |
| Industrial hygiene: | Change contaminated clothing. Application of skin-protective barrier cream recommended. Wash hands after working with substance. Work under hood . Do not inhale substance. |
| 9. Physical and chemical properties |
| Form: | crystals | |||
| Colour: | colourless | |||
| Odour: | pungent | |||
| pH value | not available | |||
| Melting temperature | 51 - 54 °C | |||
| Boiling temperature | 245 °C | |||
| Ignition temperature | not available | |||
| Flash point | 118 °C | |||
| Explosion limits | lower | not available | ||
| upper | not available | |||
| Vapour pressure | (20 °C) | 0.02 hPa | ||
| Solubility in | water | (20 °C) | insoluble | |
| ethanol | (20 °C) | soluble | ||
| ether | (20 °C) | soluble |
| 10. Stability and reactivity |
| Conditions to be avoided |
| no information available |
| Substances to be avoided |
| no information available |
| Hazardous decomposition products |
| hydrochloric acid |
| 11. Toxicological information |
| Acute toxicity |
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LD50 (oral, rat): 50 mg/kg |
| Further toxicological information |
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Toxic effect on: Lacrimal irritation due to vapours. After inhalation: Irritations of the mucous membranes, coughing, and dyspnoea. After absorption of large quantities: nausea , vomiting , drop in blood pressure , CNS disorders , narcosis Further hazardous properties cannot be excluded. |
| Further data |
| The product should be handled with the care usual when dealing with chemicals. |
| 12. Ecological information |
| Do not allow to enter waters, waste water, or soil! |
| 13. Disposal considerations |
| Product: |
| There are no uniform EC Regulations for the disposal of chemicals or residues. Chemical residues generally count as special waste. The disposal of the latter is regulated in the EC member countries through corresponding laws and regulations. We recommend that you contact either the authorities in charge or approved waste disposal companies which will advise you on how to dispose of special waste. |
| Packaging: |
| Disposal in compliance with official regulations. Handle contaminated packaging in the same way as the substance itself. If not officially specified differently, non-contaminated packaging may be treated like household waste or recycled. |
| 14. Transport information |
| Transport over land ADR/RID and GGVS/GGVE (Germany) | ||||
| GGVS/GGVE class: | 6.1 | Number and letter: | 17b | |
| ADR/RID class: | 6.1 | Number and letter: | 17b | |
| Name of material: | 1697 CHLORACETOPHENON | |||
| River transport ADN/ADNR | |||
| not examined | |||
| Sea transport IMDG | ||||||
| IMDG class: | 6.1 | UN-No.: | 1697 | Packaging group: | II | |
| Ems: | 6.1-02 | MFAG: | 740 | |||
| Correct technical name: | CHLOROACETOPHENONE,SOLID | |||||
| Air transport ICAO-TI and IATA-DGR | |||||
| ICAO/IATA class: | 6.1 | UN/ID-No.: | 1697 | Packaging group: | |
| Correct technical name: | CHLOROACETOPHENONE,SOLID | ||||
| The transport regulations are cited according to international regulations and in the form applicable in Germany (GGVS/GGVE). Possible national deviations in other countries are not considered. |
| 15. Regulatory information |
| Labelling according to EC Directives | ||
| Symbol: | T | Toxic immediately and show this container or label. |
| R-phrases: | R 25-36/37-43 | Toxic if swallowed. Irritating to eyes and respiratory system. May cause sensitization by skin contact. |
| S-phrases: | S 24-37-45 | Avoid contact with skin. Wear suitable gloves. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
| EC-No.: | 208-531-1 | EC label |
| German regulations | ||
| Water pollution class | 2 | (polluting substance) |
| 16. Other information |
| Reason for alteration |
|
Change in labelling. General update. |
