| Safety data sheet |
| According to EC Directive 91/155/EEC |
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| 1. Identification of the substance/preparation and of the company/undertaking |
| Identification of the product | ||
| Catalogue No.: | 823215 | |
| Product name: | Bromomethane for synthesis | |
| Manufacturer/supplier identification | ||
| Company: |
Merck Ltd. 9th Floor, Monterey Tower, 2170 New Petchburi Road, Bangkapi, Huaykwang, Bangkok 10320 Tel: (662) 308 - 0218 |
|
| 2. Composition/information on ingredients |
| Synonyms |
| Methyl bromide |
| CAS-No.: | 74-83-9 | EC-Index-No.: | 602-002-00-3 | ||
| Molar mass: | 94.95 | EINECS-No.: | 200-813-2 | ||
| Molecular formula: | CH3Br | ||||
| 3. Hazards identification |
| Toxic by inhalation. Irritating to eyes, respiratory system and skin. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Dangerous for the ozone layer. |
| 4. First aid measures |
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First-aid personnel: ensure self-protection! After inhalation: fresh air. If necessary, apply mouth-to-mouth resuscitation or mechanical ventilation. Oxygen mask if necessary! Immediately summon doctor. After skin contact: wash off with plenty of water. Dab with polyethylene glycol 400. Immediately remove contaminated clothing. After eye contact: rinse out with plenty of water for at least 10 minutes with the eyelid held wide open. Immediately summon eye specialist. After swallowing: administer liquid paraffin, avoid vomiting (risk of aspiration!). Immediately summon doctor. |
| 5. Fire-fighting measures |
| Suitable extinguishing media: |
| In adaption to materials stored in the immediate neighbourhood. |
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Special risks: |
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Practically non-combustible. Development of hazardous combustion gases or vapours possible in the event of fire. The following may develop in event of fire: bromine , hydrogen bromide |
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Special protective equipment for fire fighting: |
| Do not stay in dangerous zone without suitable chemical protection clothing and self-contained breathing apparatus. |
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Other information: |
| Cool container with spray water from a save distance. |
| 6. Accidental release measures |
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Person-related precautionary measures: Do not inhale vapours. Ensure supply of fresh air in enclosed rooms. Additional notes: Remove container from danger zone and cool with water. |
| 7. Handling and storage |
| Handling: |
| No further requirements. |
| Storage: |
|
Tightly closed. In a well-ventilated place. Away from sources of heat. At +15°C to +25°C. Accessible only for authorized persons. Requirements for storage rooms and containers: Away from combustible substances. |
| 8. Exposure controls/personal protection |
| Personal protective equipment: | |
| Respiratory protection: | Respirator. Filter A (acc. to DIN 3181) for vapours of organic compounds |
| Eye protection: | required |
| Hand protection: | required |
| Industrial hygiene: | Immediately change contaminated clothing. Apply skin- protective barrier cream. Wash hands and face after working with substance. Work under hood . Do not inhale substance. Under no circumstances eat or drink at workplace. |
| 9. Physical and chemical properties |
| Form: | gaseous | |||
| Colour: | colourless | |||
| Odour: | sweetish | |||
| pH value | not available | |||
| Melting temperature | -93.7 °C | |||
| Boiling temperature | 3.6 - 4.6 °C | |||
| Ignition temperature | 538 °C | |||
| Flash point | 194 °C | |||
| Explosion limits | lower | 8.6 Vol% | (Hommel) | |
| upper | 20 Vol% | (Hommel) | ||
| Vapour pressure | (20 °C) | 1893 hPa | ||
| Density | (0 °C) | 1.73 g/cm3 | ||
| Solubility in | water | (20 °C) | 17.5 g/l | |
| ethanol | (20 °C) | soluble | ||
| log P(oct): | 1.1 |
| 10. Stability and reactivity |
| Conditions to be avoided |
| Heating. |
| Substances to be avoided |
| alkali metals , alkaline earth metals , aluminium , zinc , magnesium |
| Hazardous decomposition products |
| in the event of fire : bromine , hydrogen bromide |
| 11. Toxicological information |
| Acute toxicity |
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LD50 (oral, rat): 214 mg/kg ; LC50 (inhalation, rat): 302 ppm(V) /8 h ; The literature data available to us do not conform with the labelling prescribed by the EC. The EC has dossiers of the manufacturers which have not been published. |
| Subacute to chronic toxicity |
| The carcinogenic potential requires further clarification. |
| Further toxicological information |
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After inhalation: pulmonary oedema , pneumonia , cyanosis , CNS disorders ( headache , nausea , spasms ) , narcosis , death Symptoms in: lungs , liver , kidneys Latency time until onset of action. After contact with substance: Burns of: mucous membranes , eyes , skin Danger of skin absorption. |
| Further data |
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Further hazardous properties cannot be excluded. This substance should be handled with particular care. |
| 12. Ecological information |
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Behavior in environmental compartments: Distribution: log P(oct):: 1.1 ; Henry constant: 632 Pa*m3/mol ; Low bioaccumulation potential. Slow degradation. Evaluation number (FRG) (fish): 5.0 ; Evaluation number (FRG) (mammal): 5 - 6 ; Ecotoxic effects: Biological effects: Highly toxic for aquatic organisms. Toxic effect on fish and plankton. Possibly persistent in water. May cause long-term adverse effects in the aquatic environment. Hazardous to the ozone layer. Risk of formation of toxic, corrosive and explosive mixtures above water surface. Forms toxic mixtures in water, dilution measures notwithstanding. Fish toxicity: L.macrochirus LC50: 4.18 mg/l /96 h ; P.reticulatus LC50: 1.2 mg/l /48 h ; Algeal toxicity: M.beryllina LC50: 4.68 mg/l /96 h ; Daphnia toxicity: Daphnia magna EC50: 2.6 mg/l /96 h ; aquatic organisms LC50: > 1000 mg/l /96 h ; Further ecologic data: Do not allow to enter waters, waste water, or soil! |
| 13. Disposal considerations |
| Product: |
| There are no uniform EC Regulations for the disposal of chemicals or residues. Chemical residues generally count as special waste. The disposal of the latter is regulated in the EC member countries through corresponding laws and regulations. We recommend that you contact either the authorities in charge or approved waste disposal companies which will advise you on how to dispose of special waste. |
| Packaging: |
| Disposal in compliance with official regulations. Handle contaminated packaging in the same way as the substance itself. If not officially specified differently, non-contaminated packaging may be treated like household waste or recycled. |
| 14. Transport information |
| Transport over land ADR/RID and GGVS/GGVE (Germany) | ||||
| GGVS/GGVE class: | 2 | Number and letter: | ||
| ADR/RID class: | 2 | Number and letter: | ||
| Name of material: | 1062 METHYLBROMID | |||
| River transport ADN/ADNR | |||
| not examined | |||
| Sea transport IMDG | ||||||
| IMDG class: | 2.3 | UN-No.: | 1062 | Packaging group: | ||
| Ems: | 2-06 | MFAG: | 345 | |||
| Correct technical name: | METHYL BROMIDE | |||||
| Air transport ICAO-TI and IATA-DGR | |||||
| ICAO/IATA class: | 2.3 | UN/ID-No.: | 1062 | Packaging group: | |
| Correct technical name: | METHYL BROMIDE - VERBOTEN | ||||
| The transport regulations are cited according to international regulations and in the form applicable in Germany (GGVS/GGVE). Possible national deviations in other countries are not considered. |
| 15. Regulatory information |
| Labelling according to EC Directives | ||
| Symbol: | T | Toxic immediately and show this container or label. |
| N | Dangerous for the environment immediately and show this container or label. | |
| R-phrases: | R 23-36/37/38-50/53-59 | Toxic by inhalation. Irritating to eyes, respiratory system and skin. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Dangerous for the ozone layer. |
| S-phrases: | S 15-27-36/37/39-38-45-59-61 | Keep away from heat. Take off immediately all contaminated clothing. Wear suitable protective clothing, gloves and eye/face protection. In case of insufficient ventilation, wear suitable respiratory equipment. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). Refer to manufacturer/supplier for information on recovery/recycling. Avoid release to the environment. Refer to special instructions/Safety data sheets. |
| EC-No.: | 200-813-2 | EC label |
| German regulations | ||
| Water pollution class | 3 | (highly polluting substance) |
| 16. Other information |
| Reason for alteration |
|
General update. Change in the chapter on toxicology. Change in the chapter on ecology. |
