| Safety data sheet |
| According to EC Directive 91/155/EEC |
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| 1. Identification of the substance/preparation and of the company/undertaking |
| Identification of the product | ||
| Catalogue No.: | 823347 | |
| Product name: | Phosgene for synthesis | |
| Manufacturer/supplier identification | ||
| Company: |
Merck Ltd. 9th Floor, Monterey Tower, 2170 New Petchburi Road, Bangkapi, Huaykwang, Bangkok 10320 Tel: (662) 308 - 0218 |
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| 2. Composition/information on ingredients |
| Synonyms |
| Carbonyl chloride |
| CAS-No.: | 75-44-5 | EC-Index-No.: | 006-002-00-8 | ||
| Molar mass: | 98.92 | EINECS-No.: | 200-870-3 | ||
| Molecular formula: | CCl2O | ||||
| 3. Hazards identification |
| Very toxic by inhalation. Causes burns. |
| 4. First aid measures |
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After inhalation: fresh air. If necessary, apply mouth-to-mouth resuscitation or mechanical ventilation. After skin contact: wash off with plenty of water. Dab with polyethylene glycol 400. Immediately remove contaminated clothing. Immediately summon doctor. After eye contact: rinse out with plenty of water for at least 10 minutes with the eyelid held wide open. Immediately summon eye specialist. |
| 5. Fire-fighting measures |
| Suitable extinguishing media: |
| In adaption to materials stored in the immediate neighbourhood. |
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Special risks: |
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Development of hazardous combustion gases or vapours possible in the event of fire. Vapours heavier than air. Formation of explosive mixtures possible with air. The following may develop in event of fire: hydrochloric acid |
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Special protective equipment for fire fighting: |
| Do not stay in dangerous zone without suitable chemical protection clothing and self-contained breathing apparatus. |
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Other information: |
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Non-combustible. Prevent fire-fighting water from entering surface water or groundwater. |
| 6. Accidental release measures |
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Person-related precautionary measures: Avoid substance contact. Ensure supply of fresh air in enclosed rooms. Procedures for cleaning / absorption: Stop flow of gas, move leaking cylinder to open air if without risk. Do not inhale vapours. |
| 7. Handling and storage |
| Handling: |
| No further requirements. |
| Storage: |
| At +15°C to +25°C. Keep away from combustible materials and sources of ignition. Accessible only for authorized persons. |
| 8. Exposure controls/personal protection |
| Specific control parameter | ||
| MAK Germany (max. workplace conc.) | ||
| Phosgene | 0.02 ml/m3 or 0.082 mg/m3 | |
| Personal protective equipment: | |
| Respiratory protection: | required Filter B (acc. to DIN 3181) for inorganic gases and vapours |
| Eye protection: | required |
| Hand protection: |
required Protective clothing should be selected specifically for the working place, depending on concentration and quantity of the hazardous substances handled. The resistance of the protective clothing to chemicals should be ascertained with the respective supplier. |
| Industrial hygiene: | Immediately change contaminated clothing. Apply skin- protective barrier cream. Wash hands and face after working with substance. Under no circumstances eat or drink at workplace. Work under hood . Do not inhale substance. |
| 9. Physical and chemical properties |
| Form: | gas | |||
| Colour: | greenish | |||
| Odour: | putrid | |||
| pH value | not available | |||
| Melting temperature | -128 °C | |||
| Boiling temperature | 8 °C | |||
| Ignition temperature | not available | |||
| Flash point | not available | |||
| Explosion limits | lower | not available | ||
| upper | not available | |||
| Vapour pressure | (20 °C) | 1616 hPa | ||
| Density | (0 °C) | 0.0045 g/cm3 | ||
| Solubility in | water | (20 °C) | (decomposition) |
| 10. Stability and reactivity |
| Conditions to be avoided |
| no information available |
| Substances to be avoided |
| alkali metals , amines , water |
| Hazardous decomposition products |
| with water : toxic gases/vapours |
| Further information |
| heat-sensitive , sensitive to moisture |
| 11. Toxicological information |
| Acute toxicity |
| LC50 (inhalation, rat): 1400 mg/m3 /30 min |
| Subacute to chronic toxicity |
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An embryotoxic effect need not be feared when the threshold limit value is observed. Animal experiments performed under conditions comparable with the workplace situation have shown the substance to be carcinogenic. |
| Further toxicological information |
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After inhalation: Irritations of the mucous membranes, coughing, and dyspnoea. damage of respiratory tract , pulmonary oedema After skin contact: Burns. After eye contact: Burns. Systemic effects: nausea , vomiting , dyspnoea , death No description of any further symptoms is avaiable. |
| Further data |
| The product should be handled with the care usual when dealing with chemicals. |
| 12. Ecological information |
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Ecotoxic effects: Quantitative data on the ecological effect of this product are not available. Further ecologic data: Do not allow to enter waters, waste water, or soil! |
| 13. Disposal considerations |
| Product: |
| There are no uniform EC Regulations for the disposal of chemicals or residues. Chemical residues generally count as special waste. The disposal of the latter is regulated in the EC member countries through corresponding laws and regulations. We recommend that you contact either the authorities in charge or approved waste disposal companies which will advise you on how to dispose of special waste. |
| Packaging: |
| Disposal in compliance with official regulations. Handle contaminated packaging in the same way as the substance itself. If not officially specified differently, non-contaminated packaging may be treated like household waste or recycled. |
| 14. Transport information |
| Transport over land ADR/RID and GGVS/GGVE (Germany) | ||||
| GGVS/GGVE class: | 2 | Number and letter: | ||
| ADR/RID class: | 2 | Number and letter: | ||
| Name of material: | 1076 PHOSGEN | |||
| River transport ADN/ADNR | |||
| not examined | |||
| Sea transport IMDG | ||||||
| IMDG class: | 2.3 | UN-No.: | 1076 | Packaging group: | ||
| Ems: | 2-08 | MFAG: | 600 | |||
| Correct technical name: | PHOSGENE | |||||
| Air transport ICAO-TI and IATA-DGR | |||||
| ICAO/IATA class: | 2.3/8 | UN/ID-No.: | 1076 | Packaging group: | |
| Correct technical name: | PHOSGENE - VERBOTEN | ||||
| The transport regulations are cited according to international regulations and in the form applicable in Germany (GGVS/GGVE). Possible national deviations in other countries are not considered. |
| EXCLUDED FROM TRANSPORT BY AIR! |
| 15. Regulatory information |
| Labelling according to EC Directives | ||
| Symbol: | T+ | Very toxic immediately and show this container or label. |
| R-phrases: | R 26-34 | Very toxic by inhalation. Causes burns. |
| S-phrases: | S 9-26-36/37/39-45 | Keep container in a well-ventilated place. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). |
| EC-No.: | 200-870-3 | EC label |
| German regulations | ||
| Water pollution class | 2 | (polluting substance) |
| 16. Other information |
| Reason for alteration |
|
Change in labelling. General update. |
